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numbers below the panels are the number of participants contributing to the mean) and estimated treatment difference for the percentage change from baseline to week 104 in body weight based on the trial product estimand

Types of Telehealth Consultations: Asynchronous (Message-Based) Consultation: Process: Complete detailed online questionnaire Upload any relevant medical records or lab results Provider reviews information within 24-48 hours Provider sends message with decision or requests more information You can ask questions via messaging Prescription sent if approved Pros: No scheduled appointment needed Complete at your convenience Often faster for straightforward cases Can take time to think about answers Cons: No face-to-face interaction Cant ask questions in real-time May feel less personal Might need additional back-and-forth messaging Live Video Consultation: Process: Schedule appointment at specific time Join video call at appointed time Live discussion with provider (15-30 minutes) Provider asks questions and reviews information You can ask questions immediately Decision made during or shortly after visit Pros: Real-time interaction Can read body language and expressions Immediate answers to questions Feels more like traditional doctor visit Provider can visually assess patient Cons: Requires scheduling specific time Need reliable internet connection Some people uncomfortable on video Slightly longer overall process Phone Consultation: Process: Schedule call time Provider calls at appointed time Discussion of medical history and goals Question and answer session Decision communicated Pros: No video needed (more comfortable for some) Can take call anywhere Real-time conversation Cons: Less common than video No visual assessment Requires scheduled time What Happens During Consultation: Provider Review: Your provider will: Assess Eligibility: Verify BMI qualifies (30+, or 27+ with comorbidities) Review medical history for contraindications Evaluate current medications for interactions Confirm no pregnancy or plans to become pregnant Check for thyroid cancer or MEN 2 syndrome history Discuss Treatment: Explain how semaglutide works Set realistic expectations for results Describe common side effects Review serious risks Discuss dosing schedule and escalation Answer Your Questions: Address concerns about injections Clarify costs and insurance Explain follow-up schedule Provide lifestyle recommendations Determine Appropriateness: Is semaglutide the right choice for you

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Another test is a gastric emptying study (scintigraphy)